Joint cavity closure, i.e. local injection of adrenocorticotropic hormones such as Methylprednisolone and Depo-Prostone, is used to relieve pain by reducing the inflammatory response. Currently, the most commonly used indications for closure are aseptic inflammation of the limb, such as tendon stop disease, that is, the junction of tendon and bone, including Achilles tendon stop disease, metatarsophalangeal fasciitis (achalasia), patellar tendon stop disease, quadriceps tendon strain, tennis elbow, golfer’s elbow, etc.; it is also suitable for tendon problems such as stenosing tenosynovitis, including trigger finger, biceps tendonitis; hormonal closure has also been widely used for soft tissue injuries, such as muscle strains, frozen shoulder, and myofasciitis. However, as the time of closure application accumulates, so do its complications!!!! The most common complication is tissue necrosis, such as the atrophy of the subcutaneous tissue of the skin caused by superficial site closure, where the skin of the area where the patient received closure is thin and the subcutaneous fat disappears, forming a deep pit, and in severe cases, this atrophy reaches all the way down to the bone, which is very unsightly. Another common complication is self-rupture of the tendon. Many orthopedic surgeons have seen ruptures of the Achilles tendon after closed treatment, often occurring about a month after the Achilles tendon is closed “hormonally”. What you get with joint cavity closure is the illusion of swelling and pain relief for a month or a few months, but what you get is total atrophy and destruction of the articular cartilage, and after a few months, the joint will be rapidly destroyed and out of control.