Tacrolimus ointment can be used for the treatment of vitiligo, the use of gently rubbed in the affected area, applied twice a day, during the use of the drug to avoid sun exposure and contact with the mucous membranes of the mouth, eyes and nose. Tacrolimus ointment belongs to the skin topical medicine, has the immunosuppressive effect, can inhibit the local inflammatory reaction, is conducive to the recovery of melanocyte function, can improve the early skin color of vitiligo. Note that during treatment, natural or artificial sunlight exposure should be minimized or avoided, even in the absence of tacrolimus ointment on the skin. It is not known whether tacrolimus ointment interferes with the skin’s response to UV damage. Tacrolimus Ointment can have side effects such as burning sensation and itching of the skin. When using it, it must be used strictly according to the doctor’s instructions under the doctor’s supervision, and it is forbidden to use it for children under two years of age, women in pregnancy, and those who are allergic to the drug. It is recommended that vitiligo patients timely to the hospital, under the guidance of the doctor standardized treatment, do not self-medication.