The healing time of proliferative erythema is related to the severity of the disease, treatment method, age and physical condition, and usually ranges from a few weeks to a few months. Proliferative erythema, also known as erythema multiforme or erythema multiforme, is a kind of precancerous lesion or carcinoma in situ that occurs in the mucosal epithelium. The cause of this disease is still unclear, mostly occurring in the glans, urethral opening, foreskin area, skin lesions are mostly manifested as a single, clear boundary, surface shiny slightly elevated bright red plaques, round, oval or irregular shape. It can be treated with topical medication, laser, cryotherapy and photodynamic therapy. The healing time is affected by the severity of the disease, the treatment program, the timing of the treatment, age, physical condition and other factors, and there may be individual differences. Topical medications are slower, mostly taking several months, and commonly used medications include fluorouracil and imiquimod, etc. They should be administered under the guidance of medical professionals. Laser, cryotherapy, photodynamic therapy and other treatments have a faster recovery time of a few weeks. If you have proliferative erythema, it is recommended that you go to the hospital in time, complete the relevant examinations, and follow the doctor’s instructions to receive treatment.