Herpes labialis is mainly to take antiviral drugs, if it causes fever, you can also use antipyretic drugs and so on. 1. Oral antiviral drugs: Herpes labialis generally refers to herpes simplex on the lips and mouth, which is a skin and mucous membrane disease caused by herpes simplex virus type I infection. Oral antiviral drugs can be taken, such as acyclovir, vasiclovir, famciclovir, etc., and those who are resistant to the above drugs can take phosphonate sodium, bromovudine and so on. 2. Antipyretic drugs: If herpes simplex causes fever, you can use aspirin, acetaminophen and so on. However, the local treatment of herpes labialis is more important, local application of antiviral drugs, such as xylocaine ointment, spray xylocaine cream, etc. The effect is also better, and for patients with severe pain, you can apply lidocaine or benzocaine. Herpes labialis should not be blindly used to avoid delaying the condition, for the use of medication should also strictly follow the doctor’s instructions, avoid self-medication.