Fire boils are boils. Fire boils and acne differ in nature, etiology, clinical manifestations and treatment. 1. Nature: Boils are acute bacterial purulent inflammation of individual hair follicles and their surrounding tissues; while acne is a chronic inflammatory disease of the sebaceous glands of hair follicles. 2. Etiology: boils are mostly caused by Staphylococcus aureus and other infections, and are related to local skin breakage, uncleanliness, and low body resistance; while the development of acne is mainly related to the elevation of androgens and the increase of sebum secretion, hyperkeratosis of follicular sebaceous gland openings, and Propionibacterium acnes infection and secondary inflammation. 3. Clinical manifestations: boils are mostly found on the head, face, neck and back, with redness, swelling, pain and hard nodules in the early stage, and then yellowish-white pus plugs may appear on the top of the boils. Acne occurs in adolescents and is common on the face. It may first appear as pimples and other conical pimples, and then develop into dark red nodules or cysts. After the inflammatory lesions subside, there is often hyperpigmentation, persistent erythema, or scarring left behind. 4. Treatment: boils are usually treated with ichthyol ointment during the red and swollen stage, and pus spots can be sterilized to remove the pus plugs, but squeezing is contraindicated. Acne patients can use retinoic acid cream, benzoyl peroxide and other topical drugs to treat, severe cases need to take erythromycin, isotretinoin and other drugs to treat, and pay attention to the affected area to clean, remove lipids. Boils and acne are both hair follicle related diseases. If severe acne or boils are accompanied by fever and generalized discomfort, they should be treated promptly, and medications should be used under the direction of a physician.