The causes of arm soreness and sleeplessness at night include subacromial impingement syndrome, frozen shoulder, cervical spondylosis and so on. According to the cause of the disease, physiotherapy, local closure, oral ibuprofen, cyclobenzaprine and other treatments. 1. Subacromial impingement syndrome: Subacromial impingement syndrome is often associated with pain in the lateral shoulder at night, which can be relieved by ice packs and localized closure, and when it is difficult to sleep at night, non-steroidal anti-inflammatory drugs such as ibuprofen and nimesulide can be taken for short-term analgesia. Usually, we should pay attention to avoid excessive lifting movement. 2. Frozen shoulder: Frozen shoulder is a chronic inflammatory injury, when you touch the shoulder at night, you can wake up with pain, and when the pain continues to be unrelieved, you can take ibuprofen, celecoxib and other non-steroidal anti-inflammatory drugs orally. Local injection of prednisolone acetate can be used when localized pain is obvious. Moderate massage, physical therapy can also relieve the symptoms. 3. Cervical spondylosis: cervical spondylosis can cause shoulder and neck pain when it stimulates the cervical nerve root, which can be relieved by bone traction, local massage, hot compresses, etc. Those who have difficulty in tolerating the pain can be treated with non-steroidal anti-inflammatory drugs such as oral ibuprofen and nimesulide, as well as muscle relaxants such as cyclobenzaprine and kalimedol. All of the above medications should be used under the guidance of a doctor, avoid self-medication. If the symptoms of arm pain at night can not sleep, it is recommended to consult a doctor in a timely manner, with the help of a doctor to clarify the cause of the disease, and targeted treatment or treatment.