Diabetes in 16-year-old girls should be timely to the regular hospital, under the guidance of a professional doctor to avoid delaying the condition. Diabetes mellitus is a group of metabolic disorders characterized by chronic hyperglycemia caused by multiple etiologies and is caused by defective insulin secretion and/or utilization. Long-term metabolic disorders can cause multi-system damage, leading to chronic progressive lesions in the heart, blood vessels, kidneys, nerves, eyes and other tissues and organs, so early diagnosis and early treatment are necessary. The treatment of diabetes mellitus includes general treatment, drug treatment and surgery. 1. General treatment: It includes healthy diet, reasonable calorie control, appropriate exercise, timely monitoring of blood glucose and complications, and evaluation of risk factors for other diseases. 2. Drug treatment: type 1 diabetes is common among 16-year-old girls, and the most commonly used treatment drug for type 1 diabetes is insulin, including short-acting insulin, intermediate-acting insulin, long-acting insulin, etc. The selection of specific drugs needs to be comprehensively judged by specialists according to the clinical situation. 3. If lifestyle intervention with or without drug therapy fails to reduce weight effectively and blood glucose control is poor, metabolic surgery can be considered. To summarize, diabetes is very harmful to the human body and must be prevented and treated early. Promote reasonable diet, regular exercise, prevent obesity, improve their physical quality and immunity. When abnormal blood glucose levels are detected, consult a doctor in a timely manner.