What are the requirements for changing the medication for diabetic foot ulcers If the diabetic foot gangrene is infectious gangrene, the medication should be changed on the basis of thorough debridement. Local redness, swelling, and pulsating sensation can be promptly incised to fully expose the degenerated tendon and gradually remove the deep inactivated tendon and necrotic tissue from the rotten tendon and penetrating ulcer. The wounded surface should be kept clean and breathable, and wet dressing with triple yellow lotion gauze should be applied. After the sinus tract is cleared of rotten tendons, medicated threads such as Jiuyi Dan and Baidan can be inserted to drain and pull out the poison, dispel the rot and create muscle. In addition, pay attention to local cleanliness and disinfection, the use of new tincture of Jellan, iodine volts, etc., a wide range of disinfection of the affected foot, especially between the toe crevices and heel chaps, in order to kill the fungus. At the same time, antifungal, anti-anaerobic Chinese and Western medicine can be selected for cleaning and external application, such as metronidazole solution, Yin Chen, bitter ginseng, alum, neem, etc. If the diabetic foot ulcer is mainly ischemic, it is enough to use topical application of decay-eliminating and muscle-generating drugs according to different conditions.