Postoperative anticoagulation in patients with valve replacement is very important, some patients do not understand the considerations of anticoagulation, here is a brief discussion of the postoperative anticoagulation to pay attention to: 1, anticoagulation and seasonal relationship. In the north, each season’s vegetables differ due to the content of vitamin k1, k3, because k1, and k3 can neutralize the anticoagulant warfarin anticoagulation, if the vegetables containing K1, K3 more consumption of too much, with a cause of anticoagulant effect decreased, anticoagulation has an impact, the doctor will be examined, according to the needs of the patient’s condition, at any time to adjust the amount of warfarin to achieve the body needs The anticoagulant effect. In general, do not be partial, normal diet has little effect on anticoagulation. Pang Yunfeng2 of the Department of Cardiac Surgery, Qinghai Cardiovascular Hospital, is related to the patient’s physical state. After taking the drug, it will be metabolized by the liver, and if the patient has problems with liver function, then the dosage will need to be adjusted to suit the body’s needs. The drug’s effect on warfarin can also be affected by colds, gastritis, or irregular diet, so it is important to keep in touch with the treating physician to adjust the medication at any time.3, and other drugs have a relationship, each drug has an effect on the effect of warfarin, only the size of the effect is different. Therefore, remind patients to read the instructions when taking any drug, such as aspirin class, antipyretic and analgesic, anti-inflammatory and analgesic drugs, all have an effect on the anticoagulant effect of warfarin. If you have a cold or take anti-cold medication for 2-3 days, it is recommended that you go to the hospital for a PT check to see if these medications have had an effect on warfarin.4. Patients who need dental, or other surgical procedures need to contact their primary surgeon to adjust the dosage of the medication. For example, if the patient is having a baby, he or she should also contact the surgeon, who will guide him or her on how to adjust and take the anticoagulant medication.5 The method of anticoagulation adjustment: 1) Insufficient anticoagulation: PT 〈16 seconds, INR 〈1.8, 1/4 or 1/8 of the maintenance amount can be added as appropriate. 2) Excessive anticoagulation: PT〉25 seconds, I NR〉3.0, then the patient should be checked for bleeding manifestations, and the medication should be suspended for a day and measured the next day. If necessary, repeat the measurement and adjustment until stable.6, Anticoagulation requirements 1): For aortic valve replacement, the standard ratio (INR) 1.5-1.8. For mitral valve replacement and bivalve valve replacement, the standard ratio (INR) 1.8-2.0. 2) After biological valve replacement, stop anticoagulation after six months.7, Patients with valve replacement, pay attention to avoid trauma, especially head trauma. What do I need to do for postoperative review of heart valve disease? The following tests are generally required: electrocardiogram, echocardiogram, radiograph, PT test, and for patients who have just undergone valve replacement surgery, the PT test should be repeated once every half month, once a month if the anticoagulation standard is met, and once every three months if the standard continues to be met.