Tadalafil 5 mg is administered orally, at least 30 minutes before sexual intercourse, with a typical dose of 10 mg at a time, which can be adjusted to 20 mg at a time, up to once a day, if it is not effective. For most patients, the recommended starting dose of tadalafil tablets on an as-needed basis is 10 mg, taken prior to sexual intercourse. Depending on individual efficacy and tolerability, the dose may be increased to 20 mg or decreased to 5 mg. The maximum recommended dosing frequency for most patients is once daily. Tadalafil tablets are not affected by food intake. Tadalafil tablets should not be broken and should be taken as a whole tablet. Tadalafil is a selective inhibitor of phosphodiesterase 5, which is used clinically to treat erectile dysfunction in men, but it does not enhance libido and requires adequate sexual stimulation to be effective. Common adverse effects of tadalafil include headache, indigestion, nausea, dizziness, and muscle pain, and may also cause sudden visual disturbances, hearing loss or absence. Tadalafil is contraindicated in people who are allergic to the components of the drug, people who have had a myocardial infarction within three months, patients with unstable angina, patients with refractory hypertension or hypotension, patients who have had a stroke within six months, patients with retinopathy, patients with severe hepatic insufficiency, underage males, and people who have lost their sexual function, as well as the use of concomitant use of nitrate drugs is prohibited. Tadalafil should be used under the supervision of a specialist.