Cranial defect is a particularly common disorder, and the presence of many external risk factors may lead to cranial defect, such as falling objects, traffic accidents and so on. Once a skull defect occurs, it will have a great impact on health, so it is generally recommended to go to the hospital for repair surgery to restore the integrity of the skull as soon as possible to avoid further damage. However, in the process of skull repair surgery, the use of repair materials is very critical, and good materials can achieve better repair results. Currently, many local hospitals are using titanium mesh material for surgery, which is much more advanced than traditional materials, but there are still some unavoidable problems. For example, titanium mesh material is a metal material, which will affect the post-operative CT MRI and other examinations; poor insulation, the patient is sensitive to hot and cold environment; titanium mesh material is not very good tissue compatibility, post-operative rejection and infection may occur, or even damage to the scalp tissue, resulting in titanium mesh material exposed and so on. What should I do if the titanium mesh material is exposed? Is it better to replace titanium mesh with peek for skull repair? Obviously, in the event of severe titanium mesh exposure, the titanium mesh should be surgically removed in a timely manner and the scalp tissues should heal before surgery. At this time, it is better to replace the PEEK material because the properties of the PEEK material are very close to those of the autologous skull, and there are basically no problems with the titanium mesh material. Currently, PEEK is used for skull repair surgery for patients with skull defects, and for patients who have failed to repair their skull with titanium mesh, we use special techniques to remove the titanium mesh and place PEEK at the same time. At the same time, we continue to research and explore, technical innovation and upgrade, the introduction of the concept of aesthetic plastic surgery, post-operative recovery more beautiful, patients are unanimously praised.