Taking metformin during pregnancy can have an effect on the fetus and may lead to fetal malformations. Metformin is a hypoglycemic agent belonging to the class of biguanides, and its main effects include inhibiting the secretion of hepatic glucose and lowering the fasting blood glucose value. Metformin is not recommended for patients who are already pregnant, but insulin can be used under medical supervision to maintain blood glucose levels as close to normal as possible, thus reducing the risk of fetal malformations. Metformin is excreted in breast milk and breastfeeding is not recommended during Metformin therapy. Pregnant women should follow the doctor’s instructions to standardize the use of medication during pregnancy and avoid self-medication, which may affect the fetus. Pregnant women during pregnancy should pay attention to do a good job of prenatal checkups, actively listen to the advice of professional doctors to do a good job of comprehensive care and health care, pay attention to rest, at the same time, should relax, to avoid nervousness, anxiety, any discomfort should be timely to the hospital, by the doctor to clarify the diagnosis, and cooperate with the doctor to deal with the symptoms.