Early symptoms of nephrotic syndrome can be manifested as massive proteinuria, hypoproteinemia, edema, hyperlipidemia and other symptoms, and some patients can also be accompanied by systemic symptoms such as decreased appetite. 1. Massive proteinuria: It is mainly due to the impaired barrier effect of glomerular filtration membrane, which increases the protein content in the urine, and the patients mainly show the increase of foam in the urine, which is large and dense, and not easy to go down. 2. Hypoproteinemia: due to the large amount of protein loss, promote the compensatory synthesis of albumin by the liver to increase, when the liver synthesizes protein out of compensation, it can cause hypoproteinemia, resulting in malnutrition and growth retardation. 3. Edema: Hypoproteinemia leads to a decrease in plasma osmotic pressure, prompting water to enter the interstitial fluid, and the activation of the renin-angiotensin-aldosterone system leads to water and sodium retention, which together lead to tissue edema, which occurs in the low-hanging parts of the body and eyelids and leads to weight gain due to excessive fluid retention in the body. 4. Hyperlipidemia: Hypercholesterolemia and/or hypertriglyceridemia, often coexisting with hypoproteinemia. Hypercholesterolemia is primarily associated with increased hepatic synthesis of lipoproteins. Hypertriglyceridemia is mainly due to catabolic disorders, with increased hepatic synthesis as a secondary factor. 5. Systemic symptoms, such as loss of appetite, abdominal distension, fatigue and fever. If you suspect the presence of nephrotic syndrome, you should go to a regular doctor in time, under the guidance of the doctor to clarify the diagnosis of the disease, and follow the doctor’s instructions to carry out the appropriate treatment.