For ABO hemolysis, there is no uniform standard for monitoring and treatment. Some scholars suggest that the test can be done once before pregnancy, the second test at 16 weeks of gestation, the third at 28 weeks of gestation, and then rechecked every 2 weeks. Most pregnant women can produce antibodies after 28 weeks, and the test is done once a week after 8 months of pregnancy. If during pregnancy preparation, the blood types of the male and female partners can be used to initially determine if there is a possibility of ABO hemolysis in the fetus. If the mother’s blood type is O and the father’s blood type is A, B or AB, the resulting fetus may develop neonatal hemolytic disease, which may lead to anemia or hypoxia. However, not all women with blood type O and men with blood type A, B or AB will have neonatal hemolysis, so there is no need to be too nervous. If you wish, you can have your blood tested for antibodies and if the potency of the antibodies is low, you can conceive without fear. If the potency of the antibodies is high, they can be lowered by oral medication, but the efficacy of current medication is not very satisfactory. In addition, ultrasound examination can also help to detect fetal hemolysis. When the fetus is found to have skin edema, fluid in the chest and abdomen, enlarged liver and spleen, or enlarged placenta, the possibility of maternal-fetal blood group incompatibility should be considered. During pregnancy, we need to actively cooperate with the examination. After the birth of the fetus, we can keep the umbilical cord blood to detect whether the fetus has neonatal hemolytic disease for timely diagnosis and treatment. ABO hemolysis in newborns can occur, but the chance of occurrence is not high, so you need to keep a happy mood during pregnancy to avoid excessive anxiety and stress affecting your own health and that of the fetus. Ensure a balanced diet and avoid greasy and stimulating foods. Regular pregnancy check-ups and treatment if necessary.