Acid reflux and drooling may be caused by physiological factors such as diet, as well as pathological factors such as peptic ulcer, chronic gastritis and gastroesophageal reflux disease. 1. Physiological factors: Certain bad dietary habits, such as overeating, irregular diet, alcoholism, etc., or eating more spicy, sweet, greasy and other stimulating or indigestible food, will stimulate the gastric acid secretion, which may cause acid reflux and drooling. 2. Peptic ulcer: patients usually accompanied by increased secretion of gastric acid, acid reflux, resulting in drooling, while the patient will also be accompanied by abdominal pain and bloating and other discomforts, and abdominal pain is usually cyclical (usually easy to develop during seasonal changes) or rhythmic (gastric ulcer patients usually pain after eating, duodenal ulcer patients usually hunger pains, most of which occur at night). 3. Chronic gastritis: it refers to the chronic inflammation of the gastric mucosa, and the secretion of gastric acid will be increased in patients, resulting in acid reflux, hypersalivation, and may be accompanied by belching (burping), nausea and vomiting, abdominal pain, loss of appetite and other discomforts. 4. Gastroesophageal Reflux Disease (GERD): It is mostly caused by impaired anti-reflux structure and function of the esophagus, decreased clearance ability or Helicobacter pylori infection, etc. Its typical symptoms are reflux and heartburn, which also lead to hypersalivation. Patients are also usually accompanied by symptoms such as burning sensation in the abdomen, belching, difficulty in swallowing, and even extra-esophageal symptoms such as cough, sinusitis, pharyngitis and asthma. If the patient has long-term or recurrent acid reflux drooling, it is recommended to seek timely medical attention to identify the cause of the disease and carry out targeted treatment to avoid delaying the condition.