ANCA-associated glomerulonephritis is very serious. ANCA-associated glomerulonephritis can affect any age and may present with fever, fatigue, bone and joint pain, and weight loss. The cause is unknown and the gradual process can involve all systems of the body. ANCA-associated glomerulonephritis requires glucocorticoid shock therapy combined with immunosuppressive therapy, such as methylprednisolone and cyclophosphamide, and renal replacement therapy in clinical management. If left untreated it can progress to irreversible renal failure with a mortality rate of up to 80% within one year. ANCA-associated glomerulonephritis is a serious disease with a poor disease prognosis, and the course of the disease may alternate between relapse and remission. Patients are advised to visit the hospital in time and follow the doctor’s instructions. At the same time, keep a good attitude and actively cooperate with doctors, early regular treatment is the key to improve the prognosis.