Drinking coffee with the rabies vaccine will not affect its effectiveness, but strong coffee is not recommended for those who are vaccinated. After rabies vaccination, antibodies to the rabies virus are formed in the body, which can protect the body against the chance of contracting the rabies virus. The ingredients in coffee do not affect the effectiveness of rabies vaccination. Only some people will experience nausea, vomiting, loss of appetite and other discomforts for a short period of time after rabies vaccination. Doctors will advise the vaccinated to eat more light and easy-to-digest food so as not to aggravate the body’s adverse reaction. However, it is not recommended to drink too strong coffee, because the caffeine content of strong coffee is relatively high, which will stimulate the mucous membrane of the gastrointestinal tract, and will easily cause discomfort. After the rabies vaccination should also observe the body’s condition, if the adverse reaction is more serious, you need to communicate with the vaccination doctor in a timely manner, combined with the physical condition of the body to take corresponding measures to adjust.