Nevus of Ota is another “black” birthmark that is more common in children. Because of the deep pigmentation, most children have a “cyanotic” clinical presentation, so it is also known as a brownish cyanotic nevus on the palate of the eye. About 50% of the children have it after birth, while others have it within one year of age, and occasionally it appears later or during pregnancy. 2. The birthmark is located in the distribution area of the trigeminal nerve on the face, often involving the upper and lower eyelids, zygomatic area and temporal area on one side of the face, and some babies can be involved in the sclera on the same side, so most parents will prompt the doctor that the child “has a blue patch in the white eye”. If the lesions are extensive, they may even spread to the cheeks, forehead, scalp, nose and ears. Occasionally, the lesions may be bilateral. 3.The lesions are brown, greenish-gray, blue, black or purple patches, which can be distributed in a network or map-like pattern, and occasionally nodules appear. 4.Most of them do not heal on their own, and there may be a risk of aggravation at puberty. 5. If the nevus is located in the shoulder, upper arm, posterior supraclavicular and lateral arm innervation areas, i.e., the shoulder and upper arm deltoid area, it is clinically called “Ito nevus”. Both nevus of Ota and nevus of Ito can be treated with 694nm Q-switched ruby laser, 755nm Q-switched emerald laser or 1064nm Q-switched Nd:YAG laser. Generally, 3-6 treatments are needed, with an interval of about 3 months each.