With the change of dietary taste and the natural degradation of human taste, people’s taste is getting heavier and their salt intake is increasing. There is no evidence of a direct relationship between a high-salt diet and male reproductive function, but a long-term high-salt diet can induce hypertension, diabetes, gastric disease and kidney function impairment, posing a great risk to people’s health and can indirectly damage the reproductive system. Long-term high salt diet is the main cause of hypertension and may lead to cardiovascular disease. The expression of endothelial nitric oxide synthase (eNOS) in both testicular spermatogenic and supporting cells of rats with hypertension was higher than that in normal testicular tissue, but testosterone levels decreased with the increase of blood pressure. eNOS can catalyze the synthesis of nitric oxide (NO), an endothelial-derived diastolic factor with an important role in vasodilatation and regulation of blood pressure in the body. Low concentrations of NO help increase sperm motility, reduce lipid peroxidation and improve sperm fertilization, while high concentrations of NO have damaging effects on sperm. High levels of eNOS in the testes of men with hypertension can catalyze the production of high levels of NO, which impairs sperm function; secondly, low levels of testosterone may also impair male fertility by affecting the reproductive endocrine axis. High salt intake is also correlated with obesity. An increase in salt intake of 1g per day can increase the risk of obesity in adults by about 26%. Obesity is closely related to insulin resistance and disorders of lipid metabolism in the body. Hyperinsulinemia can cause sperm impaired energy acquisition and energy imbalance, and hyperlipidemia often leads to abnormal sperm structure and morphology, reducing sperm count and vitality. Secondly, obesity can also lower testosterone levels, increase estrogen levels and increase pro-inflammatory factors in men, ultimately causing a decrease in sperm count, decreased vitality and morphological changes, which can damage male fertility and even lead to infertility. Men who consume high salt diet for a long time can induce obesity, which can indirectly affect male reproductive function through the above mechanism. Long-term intake of high-salt diet can further induce dysfunction of several organs in the body, indirectly affecting male fertility, how much salt is appropriate to eat every day? The Chinese Nutrition Society recommends a daily salt intake (including soy sauce and other food salt) of 6 g for healthy adults, and for men with fertility needs, attention should be paid to controlling salt intake daily to maximize the protection of body functions and fertility.