Numbness and pain in the limbs consider intervertebral disc herniation, spinal cord cervical spondylosis, radiculitis, diabetic neuropathy and other reasons, for the cause of the disease to take medication, physical therapy or surgical treatment. 1. Herniated intervertebral disc: compression of cervical intervertebral disc herniation can cause pain and numbness in the upper limbs, and compression of lumbar intervertebral disc herniation can cause pain and numbness in the lower limbs, which can be treated by cervical traction, acupuncture, neuromuscular stimulation, and application of nutritive drugs such as methylcobalamin, and oral non-steroidal painkillers, such as Diclofenac Sodium Enteric-coated Tablets or Celecoxib Capsules. 2. Spinal cord cervical spondylosis: numbness and pain in the limbs caused by spinal cord compression and edema, applying dehydrating and swelling drugs, such as mannitol injection or sodium heptaphyllosaponin for injection, and adopting spinal decompression and nerve relaxation surgery when the conservative treatment is not effective. 3. Radiculitis: Nutritional nerve drugs such as methylcobalamin and hormonal drugs such as prednisone acetate can be applied. 4. Diabetic neuropathy: control blood sugar in the normal range, under the guidance of the doctor to apply nutritive nerve drugs such as lipoic acid and methylcobalamin. So numbness and pain in the limbs should be timely medical treatment, for the cause of the treatment, under the guidance of the doctor to choose drugs.