How to read hepatitis B half results

Judgment of a hepatitis B two pairs of half test, can be divided into two steps to see: the first step to determine the results of this test is normal or abnormal To solve this problem just look at the first two can, if the first surface antigen (HBsAg) positive, the results of this test is abnormal; and the second surface antibody (HBsAb) positive, the results of this test is normal. Why? Because HBsAg positive indicates that the patient has been infected by the hepatitis B virus, is the current hepatitis B virus infection, that is, with hepatitis B, chronic hepatitis B virus carriers and other diseases; while HBsAb positive indicates that the body has immunity to the hepatitis B virus, not only now no hepatitis B and will not be infected by the hepatitis B virus, this test result is of course normal. When HBsAb is positive, the first HBsAg and the third HBeAg must be negative, while the fourth HBeAb and the fifth HBcAb can exist for a period of time after the body has become immune to the hepatitis B virus, they are positive or negative does not affect the judgment of this test is normal. The second step is to determine whether the test results are highly infectious or less infectious, which is often referred to as hepatitis B major or minor triplets. For a surface antigen (HBsAg) positive test, to determine whether it is hepatitis B major or minor triple-positive mainly depends on the third e antigen (HBeAg) and the fourth e antibody (HBeAb). The third e antigen (HBeAg) positive test sheet is hepatitis B major third-positive; the fourth e antibody (HBeAb) positive test sheet is hepatitis B minor third-positive. Generally speaking, hepatitis B major triple-positive indicates greater contagiousness, and hepatitis B minor triple-positive indicates less contagiousness. The first three items of the hepatitis B half test are negative, but the fourth item of e antibody (HBeAb), the fifth core antibody (HBcAb) alone or at the same time appear positive. This situation occurs from time to time in the physical examination, it is generally believed that there are often the following possibilities: 1, about 30% is false positive; 2, part of the chronic hepatitis B virus carriers, that is, hepatitis B “small three positive” patients, because the surface antigen (HbsAg) load is low, so that the current detection method is difficult to detect its presence; 3, may be the hepatitis B virus infection. The surface antibody will turn positive after a period of time; 4, it may be a person who is already immune to hepatitis B virus, but after a period of time the surface antibody (HBsAb) titer decreases to the point that it is undetectable. Once the hepatitis B virus has attacked, the body will produce surface antibodies again to defend against infection through a recall response. In rare cases, the first surface antigen (HBsAg) and the second surface antibody (HBsAb) appear positive at the same time. This should be considered as a result of infection with two different subtypes of hepatitis B virus. If only the third e antigen (HBeAg) or the fourth e antibody (HBeAb) is positive, it is usually due to laboratory error, as the e system of the hepatitis B virus is more prone to false positives. Finally, it should be noted that only the interpretation of the hepatitis B two pairs of half of the test here, to determine the size of the infectious in combination with the HBV-DNA load, but that is beside the point.