Lumbar pain after 2 years of lumbosacral spinal fusion may be caused by loose internal fixation, unfused vertebrae, lesions of neighboring vertebrae, etc. Physiotherapy, medication and surgery should be chosen according to the specific causes. 1. Loosening of internal fixation: Postoperative excessive activities or weight bearing can cause the loosening and displacement of internal fixation, stimulate the vertebral body or the surrounding soft tissues, resulting in lumbar pain, should be checked in a timely manner in the hospital, and once it is clear that there is a loosening and displacement of internal fixation, it is necessary to carry out surgical treatment as early as possible, and remove the internal fixation in a timely manner. 2. Vertebral body is not fused: due to premature postoperative activities or accompanied by chronic diseases such as osteoporosis, diabetes, etc., can lead to vertebral body is not completely bony fusion, the need for timely hospital examination, if it is clear that the vertebral body has not reached the bony fusion, then need to carry out a second operation, once again, bone graft fusion. 3. Neighboring vertebral lesions: Neighboring vertebral lesions can also lead to lumbar pain, patients should try to rest in bed, avoid bending labor, can follow the doctor’s instructions to use diclofenac sodium, celecoxib and other drugs to relieve pain, as well as vitamin B, methylcobalamin and other drugs such as nutrient nerves. Lumbosacral spine fusion surgery after 2 years of lumbar pain, it is recommended that the patient timely hospital consultation, a detailed examination, according to the cause of targeted treatment, usually recommended more rest.