One month before the death of rectal cancer, distant metastasis of cancer cells has occurred, the signs and symptoms are the symptoms of advanced rectal cancer, which are divided into local and systemic symptoms. Local symptoms 1. Change of stool shape and defecation habit: In late stage of rectal cancer, the growth rate of tumor becomes faster and faster, and patients’ defecation will show more frequent stools, unformed stools, pus and blood stools, mucus stools, and even more serious black stools, which are characterized by acute and posterior weight; 2. Abdominal pain: In late stage of rectal cancer, abdominal pain will be progressively aggravated, and continuous dull pain and colic will appear. Intestinal obstruction: when rectal cancer is advanced, there will be obvious intestinal obstruction and abdominal mass, and intestinal obstruction is due to the increase of tumor volume, resulting in the narrowing of intestinal cavity, with the aggravation of obstruction, there will be constipation, abdominal distension, abdominal pain and other symptoms, and also intestinal sounds; 2. Symptoms, such as anemia, emaciation, weakness, fever and cachexia, etc.; 2. The survival time of patients with advanced rectal cancer is relatively short. If necessary, some pain relieving drugs can be used to relieve patients’ pain, eliminate patients’ fear psychology, try to meet patients’ reasonable needs, improve patients’ quality of life and reflect certain humanistic care.