Chest pain in the emergency room is a common problem, and every complaint of chest pain seen at night needs to be carefully identified, but with the limited energy of your overnight shift, is there a loss of judgment? It is only by grasping the main points that you can not miss every doubt, read these points together. Ischemic cardiogenic pain originates from visceral pain, mainly manifested as involvement pain, no response to position change, no significant response to food or type and amount of fluid intake. There is no pressure pain, but there is a response to nitroglycerin treatment. Non-ischemic cardiogenic pain is also of visceral origin and presents as referred pain, with no effect on postural changes or activities, no effect on the type of food or oral fluids consumed, no local pressure pain, and no response to nitroglycerin treatment. Pulmonary disease: The type of pain is visceral or superficial, usually without involvement pain, no significant effect of position change or movement, no effect of food or oral fluid type on chest pain, no local pressure pain. Nitroglycerin is not effective. Pneumothorax: The pain type is also visceral type or body surface type, no involvement pain, no obvious effect of position change or exercise on the symptoms of pneumothorax, no change in the nature of food and oral fluid on the chest pain, usually no obvious local pressure pain. Nitroglycerin contained is not effective. Skeletal muscle problem: The type of pain is superficial and does not have the manifestation of involvement pain, and the symptoms can be aggravated by postural changes or exercise. Nitroglycerin is not effective. Gastrointestinal problems: The type of pain is visceral, sometimes with involvement pain, and is not significantly affected by postural changes or exercise, and in some patients, the characteristic forced position helps to relieve abdominal symptoms, but the relief of chest pain is not obvious. The type of food and the nature of oral fluids have some influence on the symptoms of chest pain, and there is no local pressure pain manifested in chest pain. Nitroglycerin contained is not effective. Aortic aneurysm or entrapment: the type of pain is visceral type, generally with involvement pain, no obvious effect of position change or movement, no change of food type and nature of oral fluid on chest pain, no local pressure pain. Nitroglycerin is not effective. Mental factors: The pain type is visceral type or body surface location variable type, generally does not have the manifestation of involvement pain, position change or movement does not have obvious effect, food type and oral fluid nature does not change the chest pain, and there is no local pressure pain. Nitroglycerin is not effective.