Whether urine occult blood and urine leukocyte positive is kidney disease mainly depends on the cause of urine occult blood and urine leukocyte positive. If it is caused by urine pollution or coagulation dysfunction, etc., it is not kidney disease at this time; if it is caused by interstitial nephritis and other diseases, it is considered as kidney disease at this time. If urine pollution, female menstruation, or coagulation dysfunction, anticoagulant overdose, etc., may lead to urine occult blood and urine leukocytes positive, renal function and urinary ultrasound and other related tests are not abnormal, this situation is usually not kidney disease. If it is interstitial nephritis, can be manifested as microscopic hematuria, sterile leukocyturia, etc., urine occult blood and urine leukocyte positivity, this is considered to be kidney disease, need further treatment. Urine occult blood and urine leukocyte positive may also have other reasons, it is recommended that patients go to the regular hospital in a timely manner, complete the examination to determine the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.