The worst outcome of chest congestion with variant asthma is life-threatening multi-organ failure, which can be followed by respiratory failure after chest congestion and dyspnea. Respiratory failure can cause disturbance of acid-base balance, resulting in respiratory acidosis leading to electrolyte disturbance, such as hypokalemia, which can also induce cardiac arrhythmia and cardiac arrest. If the patient has respiratory distress, it is recommended to go to the hospital promptly and if there is respiratory failure after blood gas examination, ventilator mechanical ventilation treatment is needed to significantly relieve the symptoms and save the patient’s life.