Boils are generally referred to as boils in clinical practice. The differences between boils and acne include causes, symptoms, and treatment. 1. Causes: The causes of boils are mostly related to Staphylococcus aureus infections and high temperature environments, while the causes of acne are mostly related to increased androgen levels, Propionibacterium acnes infections, as well as overproduction of sebaceous glands and abnormal keratinization of follicular openings. 2. Symptoms: Boils are usually characterized by one or more red, hemispherical, painful nodules, which can occur anywhere on the body and can develop into carbuncles; acne is often characterized by pimples, papules, and pustules, and occurs in areas with dense sebaceous glands. 3. Treatment: boils are usually treated with antibiotics, such as mupirocin and fusidic acid, which have antibacterial and antimicrobial effects; acne is mainly treated with retinoids, such as adapalene and tazarotene, which help to dissolve pimples and fight inflammation, and if the condition is serious, it can be combined with antibiotics, such as doxycycline, to treat the condition. The difference between boils and acne is not one and the same, it is recommended to consult a doctor at a regular hospital and follow the doctor’s instructions for treatment.