Whether the left descending colon inflammatory exudative changes is serious or not needs to be judged according to the etiology, condition and other factors, if the left descending colon inflammatory exudative changes is caused by colitis, colon polyps and other diseases is generally not serious, if it is caused by colon cancer, it is generally more serious. Descending colon is a part of the colon, the left side of the descending colon inflammatory exudative changes refers to the inflammation of the blood vessels permeability changes, so that the blood vessels in the components of its infiltration into the tissue interstitial space, there may be mucosal congestion and edema, mucosal roughness, erosion and other phenomena. If the left descending colon inflammatory exudative changes caused by colitis, colon polyps and other diseases, generally less serious, through drug treatment, surgical treatment, etc., the general prognosis is good. If the inflammatory exudative changes on the left side of the descending colon are caused by malignant tumors such as colon cancer, it is usually a more serious case, and if it is not treated in time, metastasis is likely to occur, affecting the patient’s daily life. Inflammatory exudative changes in the left descending colon should be identified as the cause of the disease and treated under the guidance of a doctor.