50-year-old patients with cirrhosis for 30 years should follow the doctor’s instructions for standardized treatment, such as drug treatment, abdominal puncture, etc., but also need to maintain a healthy lifestyle and diet. 50-year-old patients with cirrhosis for 30 years should follow the doctor’s instructions to use adenosylmethionine, ursodeoxycholic acid and other drugs to protect the liver; patients with hepatitis B can use entecavir and other drugs to treat; patients with ascites can use furosemide, spironolactone and other medications to treat, and can be carried out peritoneal puncture to release ascites if necessary. In daily life, patients with liver cirrhosis are advised to maintain a light diet, with less salt, less oil and less sugar as the main focus. Patients with esophagogastric fundal varices should also avoid eating rough and hard foods, such as cookies, coarse grains, ham, etc., and avoid drinking alcohol to maintain a good life style. Patients aged 50 who have been diagnosed with cirrhosis for 30 years should actively cooperate with their doctors in treatment, and maintain a good mindset and a healthy lifestyle, all of which will help to improve the prognosis.