Isotretinoin has the potential to injure the liver. Isotretinoin is indicated for severe refractory nodular acne, adverse reactions, and may cause elevated alkaline phosphatase, so there is a risk of drug-related liver injury. Adverse reactions: there is also the possibility of allergic reactions, tachycardia, as well as triglyceride abnormalities, fluctuations in blood glucose, is likely to cause bleeding gums, esophagitis, nausea, vomiting, anemia, thrombocytopenia, etc., and secondly, there is a possibility that it may also lead to dizziness, fatigue, drowsiness, etc.. Contraindications: prohibited for those who are allergic to the ingredients, prohibited for use in women who are pregnant or are about to become pregnant, prohibited for lactating women with liver or kidney insufficiency, patients with vitamin A overdose. The body has a disease, you need to go to the hospital in time to check, under the guidance of the doctor to use the drug.