Dilatation of the submandibular gland is considered to be related to submandibular inflammation, mumps, sublingual gland cysts, etc. It can be treated with medication or surgery as prescribed by the doctor. 1. Submandibular gland inflammation: the patient may have a dilated submandibular gland due to localized infection. Usually, patients can be treated with antibiotics such as penicillin and ceftazidime, and those with pain can be treated with non-steroidal anti-inflammatory drugs such as ibuprofen and acetaminophen. In addition to medication, surgical treatment such as removal of submandibular gland is also feasible. 2. Mumps: some patients will have the phenomenon of submandibular gland expansion, some patients in the early stage of the disease can be prescribed to use ribavirin and other antiviral drugs, pain can also be prescribed to take acetaminophen, ibuprofen relief. For severe headache and vomiting, 20% mannitol can be injected intravenously to relieve the purpose. 3. Sublingual gland cyst: the disease can also cause some patients with submandibular gland expansion. Usually, patients can follow the doctor’s prescription of paxillin sclerotherapy, but also through pouching, sublingual gland gland removal surgery and other surgical methods of treatment. Some patients may also be treated with laser therapy or cryotherapy. Cysts and stones in the submandibular gland can also cause submandibular gland dilatation, and it is recommended that the patient be examined in order to identify the disease and then follow the doctor’s instructions for treatment. Usually, the dilatation of the submandibular gland can be reduced or disappear after treating the cause.