Salmeterol side effects can be manifested in the cardiovascular system such as angina pectoris, arrhythmia, nervous system such as headache, tremor, digestive system such as dry mouth, nausea and so on. 1. Cardiovascular system: Salmeterol is a β-adrenergic receptor agonist, and its side effects are mainly related to its pharmacological effects, such as angina pectoris, arrhythmia, tachycardia, palpitations, convulsions, angina pectoris, hypertension or low blood pressure. 2. Nervous system: muscle tremor, limb cramps, headache, dizziness, insomnia and so on. 3. Digestive system: dry mouth, nausea, dizziness, fatigue, depression and insomnia, cardiac arrest or even death that may be triggered by the abuse of Salmeterol. In conclusion, if any discomfort occurs during the application of Salmeterol, it is necessary to consult a doctor in time and treat the cause under the guidance of a specialist.