Drinking red wine does not affect the nucleic acid test the next day. Most of the new coronavirus nucleic acid test is conducted by nasal swab or pharyngeal swab, through the use of sampling swabs in the subject’s pharynx and nasal cavity to collect mucous membrane parts of the secretion specimen, and then carry out the PCI nucleic acid test. Red wine is a volatile liquid whose main component is ethanol, which normally enters the gastrointestinal tract normally to be broken down and digested. If some alcohol is retained in the throat of the subject, it cannot affect the reproduction or even inhibit the level of the virus. In particular, after the subject’s breathing activity, the amount of alcohol in the body are gradually evaporated, the residual amount is very small, and generally will not affect the results of the subject’s nucleic acid test. In conclusion, a small amount of red wine does not affect the nucleic acid test the next day, but drinking alcohol is harmful to health, try to avoid drinking alcohol before the nucleic acid test.