Case: 74-year-old Auntie Zhou suffered from diabetes and hypertension for many years. She was worried that once she went to the doctor, she would not be able to stop the medication for the rest of her life, so she never had regular consultation and treatment. Six months ago, Auntie Zhou had recurrent angina and her symptoms worsened with a little activity. This time she was in a hurry and rushed to the hospital, where the doctor diagnosed her with coronary artery disease, unstable angina, diabetes and hypertension and advised her to be hospitalized for further examination and treatment. However, she immediately refused to undergo coronary angiography, which might require stent placement, and only requested medication. She thought that the chest pain would not be life-threatening and would be relieved with rest. The doctor who saw her repeatedly failed to persuade her, so he could only advise her to take her medication regularly and to seek medical treatment for acute attacks of chest pain in time. Shortly after, Auntie Zhou’s recurrent chest pain attacks worsened for 3 days, and she went to the hospital again after 15 hours of continuous chest pain with cold sweats and shortness of breath. According to her family, Auntie Zhou had been trying to stay up a little longer to see if she could pull through. When she arrived at the emergency room, Auntie Zhou’s pulse and blood pressure could not be measured. The doctor quickly made a diagnosis and started a green channel for emergency PCI for heart attack, and emergency imaging found that all three vessels of the coronary arteries were occluded. Although the cardiologist quickly opened the infarct-related artery and applied the best treatment in a very short time, she died 2 days later from cardiogenic shock due to untimely treatment. We all hope that Auntie Zhou’s tragedy will not happen again, so we remind everyone of the following points. First, when found suffering from hypertension, diabetes and other diseases, must pay attention to the treatment under the guidance of a specialist, not to avoid the disease. This can minimize the occurrence of adverse consequences such as myocardial infarction. Second, when symptoms such as angina pectoris occur, a scientific and reasonable diagnostic assessment should be made with the help of a cardiovascular specialist, and depending on the situation, either simple drug therapy or blood flow reconstruction plus drug therapy should be chosen. Early intervention on ischemic myocardium can reduce the risk of death. Third, once symptoms such as persistent chest pain occur, seek medical attention at the first opportunity. “Time is heart muscle, time is life”, and the prognosis is often poor if the best time for reperfusion of myocardial infarction is missed.