Pimples around the anus are considered to be caused by hemorrhoids and anal eczema, especially hemorrhoids, which are prone to the formation of venous blood clots due to impaired venous blood return around the anus, especially thrombosed external hemorrhoids. Usually, the formed pimples cause painful sensation in the anal area and discomfort during defecation. Anal eczema can also cause acne around the anus. The appearance of anal eczema is mainly caused by the dysfunction of one’s own endocrine function and the long-term humidity of the environment around the anus. Anal eczema can lead to tiny papules on the skin around the anus, which can cause itching symptoms. In addition to these causes, allergic dermatitis and viral infections caused by sexually transmitted diseases, such as condyloma acuminata, can also cause acne around the anus.