The jejunostomy tube pus can be treated by changing drugs, medication, surgical treatment and other ways of treatment. 1. change the medicine: the jejunostomy tube pus situation, the local need to change the medicine treatment every day, keep clean and dry around the fistula, pay attention to the nursing period, avoid getting wet or scratching, so as not to aggravate the infection. 2. medication: jejunostomy tube pus, if there is local pain, fever and other symptoms, it is recommended to go to the hospital in a timely manner, under the guidance of the doctor to apply systemic antibiotic anti-infection treatment, such as taking amoxicillin clavulanate potassium tablets, clarithromycin capsules, etc., the infection can be serious intravenous ceftriaxone sodium, levofloxacin and other antibiotic treatment until the inflammation is controlled. 3. Surgery: If the above treatment is not good, it is recommended to arrange according to the condition, surgical resection of necrotic tissue, re-establishment of fistula. If the jejunostomy tube pus continues to be unrelieved, it is recommended to go to the hospital in time, under the guidance of the doctor targeted treatment, to avoid delaying the condition, resulting in other damage.