Gout is an ancient disease. It was described more than 2,000 years ago in ancient Greece, in the time of Hippocrates, as a disease of acute swelling and pain in the joints that came and went suddenly. Due to medical limitations, it was thought that an evil fluid dripped into the joint cavity and caused the joint pain. Over the centuries, it has been observed that joint pain often comes on after a good meal or drink. Eating and drinking were the triggers for the onset of many patients. The incidence of gout is significantly higher in those who live in privileged conditions. In ancient and modern history, many leaders and celebrities have suffered from gout, such as Alexander the Great, King Louis VII and Louis XIV of France, Queen Anne of England, President Franklin of the United States, Emperor Kublai of China, religious leaders Martin Luther and John Calvin, as well as famous scientists Newton and Harvey, and the great British literary scholar Milton, all suffered from gout. Therefore, people used to think that gout was a “disease of meat and wine”, “disease of wealth” and “disease of emperors and kings”. With the development of medical science, the cause of gout has become clear, it is caused by the deposition of uric acid crystals in the joint cavity and arthritis. The study of the metabolism of substances in human metabolism found that abnormal purine metabolism is the direct cause of the increase in blood uric acid. The emperors, generals, and scholars of all times were all rich people, and a lavish life was often the pleasure they pursued in life, not knowing that the rich and delicious food was high in purines, and the large amount of purine decomposition and metabolism produced large amounts of uric acid and could form urate crystals, which led to gout. Nowadays, human beings are in the modern civilized society on the eve of the 21st century, the improvement of material living standard has surpassed the era of emperors and generals, the change of people’s diet structure, the acceleration of the pace of life, has made gout is no longer the patent of the noblemen, according to the preliminary survey in some sanatoriums in Zhejiang, Wuhan and other places in China, in the cadres and intellectuals above 50 years old, gout patients have reached about 1%, the attack of gout has been The gout attacks have been increasing year by year, gout will become the focus of medical research as a common, multi-morbidity in modern civilized society.