Non-atrophic gastritis with celiac disease after taking a lot of drugs with poor results can be under the guidance of the doctor, through general treatment, drugs (esomeprazole, lactobacillus, etc.), surgery and other methods of treatment. 1. General treatment: it is necessary to pay attention to the supplementation of a variety of nutrients, eat less pickled, smoked, nitrate-rich and nitrite-rich food, eat more fresh food, avoid too rough, spicy food, maintain a good psychological state and enough sleep. 2. Drug treatment: non-atrophic gastritis with erosion can be treated by drugs under the guidance of doctors, such as esomeprazole, omeprazole, domperidone and other drugs. 3. Surgery: For the lesions that cannot be reversed by drugs with high-grade intraepithelial neoplasia, mucosal dissection can be performed under gastroscopy. It is recommended that patients go to the hospital in time, under the doctor’s diagnosis, according to the patient’s specific condition, to take targeted treatment, patients need to maintain a good state of mind, and develop good living habits.