Pregnant women diagnosed with horn pregnancy should undergo early surgical treatment according to their age, condition and ultrasound examination to remove the stumped uterus, or in case of live fetus, caesarean section should be performed first and then the stumped uterus should be removed. I. Close observation: If the patient strongly requests to keep the pregnancy, if the gestational sac is small and the fetal heart is good, and if she is fully aware that the horn pregnancy may lead to uterine rupture, hemorrhagic shock, DIC, intrauterine death and other serious complications in the middle and late stages of pregnancy, she may choose to continue the pregnancy under close observation and follow the results of blood HCG and ultrasound regularly. If the gestational sac gradually develops toward the uterine cavity, close observation and follow-up can be continued. If the gestational sac gradually protrudes outside the uterine horn, it is recommended to terminate the pregnancy as soon as possible to avoid uterine rupture. Second, medication: for patients with gestational sac ≤4cm, no obvious bleeding and those who choose to terminate the pregnancy, intramuscular injection of methotrexate can be tried to necrotize and detach the embryo. If the patient’s menopause is less than 9 days, mifepristone tablets with misoprostol tablets can also be used for medication abortion. During the course of medication, once the pregnant woman has persistent vaginal bleeding, prompt surgical treatment is recommended. 3. Surgical treatment: 1. Uterine removal: It is suitable for pregnant women who are less than 8 weeks pregnant, the uterine horn is not ruptured and the position of the gestational sac is close to the uterine cavity. Under the condition of ultrasound monitoring, the site of the pregnancy sac can be clearly observed and the residue in the uterus can be removed by using the method of negative pressure suction, which has the characteristics of simple operation, less cost, less damage and quick recovery; 2. Laparoscopic surgery: it is suitable for pregnant women with stable vital signs and no rupture of the uterine horn. This procedure is performed under hysteroscopy to remove uterine residues, and the fallopian tubes can be removed or preserved according to the situation. This method has the characteristics of less damage and faster recovery; 3. Open surgery: it is suitable for pregnant women with intra-abdominal bleeding due to rupture of the uterine horn, who need open surgery in time. For pregnant women with incidental late pregnancy with horn of pregnancy, caesarean section is preferred under the guidance of the doctor, and attention should be paid to the patient’s placental abruption and prevention of postpartum hemorrhage, etc.