Vertical lines between the eyebrows are what we call “ChuanZiLin” in daily life, mostly due to the frequent and excessive contraction of frowning muscles, which can be improved clinically by injecting Botox, hyaluronic acid, radiofrequency treatment, surgery, etc. 1. 1. Botulinum toxin injection: Botulinum toxin injection is a common method to improve dynamic wrinkles in clinic. Excessive contraction of frowning muscles will cause vertical lines between eyebrows, so Botulinum toxin can be injected to inhibit the contraction of frowning muscles and effectively change the dynamics of the vertical lines between eyebrows. 2. Hyaluronic acid injection: hyaluronic acid is the main component of hyaluronic acid, after crosslinking of large molecules of hyaluronic acid has a good filler, supportive effect, the current clinic is mainly used to fill the facial depression. Hyaluronic acid local injection filling is mainly used to improve the static brow vertical lines, i.e. the vertical lines that still appear in the center of the brow when no expression is made, and the effect is fast and precise. 3. Radiofrequency treatment: The principle of radiofrequency treatment is to act on the epidermis and dermis of the skin through high-frequency electromagnetic waves and the heat conduction it produces, so as to promote the regeneration and reorganization of collagen fibers and elastic fibers in the dermis layer, and ultimately to achieve the effect of reducing facial wrinkles and tightening the skin. Radiofrequency treatment can also be used to improve the vertical lines between the eyebrows accompanied by skin laxity. 4. Surgery: For those who have more serious wrinkles between the eyebrows and have a greater impact on their appearance, surgery can also be used to help eliminate wrinkles between the eyebrows, and commonly used surgical methods include forehead lipofilling, facial wrinkle removal, and so on. It should be noted that the causes and mechanisms of vertical lines between the eyebrows are different in each age group, corresponding to different treatment methods, and it is recommended that patients go to a regular medical institution to avoid the occurrence of adverse reactions.