Nasopharyngeal swabs and pharyngeal swabs generally refer to the new Crown pneumonia nucleic acid test, and the difference between the two is mainly due to the difference in the site of collection, the accuracy of the test, and the samples taken. 1. Nasopharyngeal swab: The sampling tool is mainly sent into the nasal cavity to collect the secretions from the nasopharynx as specimens for testing. 2. Oropharyngeal swab: The sampling tool is sent into the oral cavity to collect secretions from the oropharynx as specimens for testing. Although the collection site and the samples taken are different, they both detect the specific nucleic acid sequences of the new coronavirus to obtain the test results, and both have high sensitivity and accuracy. The choice of which method to use varies depending on the region and the hospital. It is recommended to consult the sampling personnel and requirements. Tip: The terms “new coronavirus pneumonia and new coronavirus pneumonia” mentioned in this article were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.