There is no scientific basis for the claim that the benefits of taking Angong Niuhuang Pills in hibernation. Angong Niuhuang Pills is a kind of Chinese patent medicine, which is composed of bull’s huang, buffalo horn concentrated powder, musk or artificial musk ice tablets and so on. It has the efficacy of clearing heat and removing toxins (removing heat, poison and evil qi from the body), and calming and opening the mind. It is used for the treatment of fever, evil qi into the pericardium, febrile convulsions (due to high fever causing convulsions), stroke coma and encephalitis, toxic encephalopathy, cerebral hemorrhage, sepsis see the above symptoms. The adverse reactions and contraindications of Angong Niuhuang Wan are not clear. If there is a need for medication, it is necessary to use under the guidance of a doctor to identify the evidence, and not blindly use their own medication, so as not to cause adverse consequences.