Osteoarthritis of the knee, also known as degenerative knee joint and osteophytes of the knee joint, is common in middle-aged and elderly people, and is more common in women; clinically, it is characterized by knee pain, swelling and limping after prolonged walking or after going up and down steps; symptoms such as interlocking and popping of the knee joint can occur when accompanied by degeneration of the meniscus of the knee joint; in advanced osteoarthritis, it can be characterized by persistent knee pain, accompanied by knee swelling, flexion deformity and In advanced osteoarthritis, persistent knee pain may be associated with knee swelling, flexion deformity and inversion deformity. Treatment of osteoarthritis of the knee, conservative treatment of osteoarthritis is aimed at improving the patient’s symptoms and delaying the degeneration of the joint, but cannot cure it. For people with mild symptoms or early osteoarthritis, we can use (1) change lifestyle habits, such as wearing soft-soled shoes such as travel shoes, obese patients need to lose weight, walk on flat roads during exercise, and do as little as possible to go up and down stairs and other activities. (2) medication: nutritional joint cartilage drugs such as glucosamine sulfate, etc. If there is pain, you can take painkillers such as Cilobal or loxoprofen sodium tablets, painkillers are not recommended for long-term use. (3) Intra-articular vitreous acid sodium injection, once a week, 3-6 times for a course of treatment (usually 5 times for a course of treatment), if the disease progresses or need to continue joint cavity injection treatment, usually 6-12 months repeat treatment, according to their own situation, 1-2 courses of treatment per year. (4) Knee arthroplasty is the only effective treatment for severe osteoarthritis, as it can directly relieve the patient’s painful symptoms.