According to the directions, Rigliptin can be taken at any time of the day, with or without meals. Riglitazide is a hypoglycemic drug and a dipeptidyl peptidase 4 inhibitor. It is mainly used for the treatment of type 2 diabetes mellitus. Riglitazide is able to elevate the concentration of active intestinal insulinotropic hormone, which stimulates the release of insulin in a glucose-dependent manner and reduces circulating levels of glucagon to lower glucose. Adverse reactions such as nasopharyngitis, diarrhea, cough, pain in the extremities, and headache may occur after taking Rigliptin. The drug cannot be used in the treatment of patients with type 1 diabetes mellitus or in the treatment of patients with diabetic ketoacidosis. And it is contraindicated in patients with a history of allergy to Rigliptin, such as urticaria, angioedema or bronchial hypersensitivity. The drug can be taken at any time of the day, with or without meals, and the drug needs to be used appropriately under medical supervision.