Cotrimoxazole and Montelukast should not be taken together and need to be taken about half an hour apart. Cotrimoxazole mainly contains four ingredients as Methocarbamol Hydrochloride, Narcotine, Aminophylline and Chlorpheniramine Maleate. The drug has certain effects related to asthma, phlegm expulsion, anti-allergy and cough relief, and can be used to treat asthma and other diseases. Montelukast is a leukotriene receptor antagonist, which is anti-inflammatory, effectively relieves airway spasm, reduces airway hyperresponsiveness, and can relieve wheezing, coughing, coughing, and other symptoms of asthma and other diseases. However, in view of the fact that both of them have anti-allergic effects and to avoid overlapping of drug effects, Compound Methocarbamol and Montelukast should not be taken together and need to be taken about half an hour apart. The above drugs need to be standardized and rationally applied under the guidance of professional physicians and pharmacists. If the symptoms fail to improve or even worsen gradually, you should consult a regular hospital in time and cooperate with the doctor to improve the examination and standardize the treatment.