Antibiotics cannot treat novel coronaviruses because they are mainly against bacterial infections and are ineffective in treating viruses. It is proposed in the novel coronavirus treatment protocol to avoid blind or inappropriate use of antibacterial drugs, especially not in combination with broad-spectrum antibiotics. The primary treatment for novel coronavirus is symptomatic supportive treatment, and general treatment includes bed rest, ensuring adequate calories, maintaining water and electrolyte balance, and timely monitoring of vital signs. Antiviral drugs can be applied appropriately, including chloroquine phosphate, Abidor, ribavirin, lopinavir ritonavir tablets, etc. These antiviral drugs are not recommended to be used more than three at the same time. In clinical practice, Chinese herbal medicine can be applied to identify and treat the symptoms, and its effect is better. On the basis of symptomatic treatment, we should actively prevent the emergence of various complications, and maintain the stable state of each organ function with supportive treatment.