Zhi Bai Di Huang Wan is a compound Chinese medicine and cannot be defined by coldness or heatiness. Cold and hot are terms used in Chinese medicine to describe the medicinal properties of single-flavored Chinese medicines, whereas Zhi Bai Di Huang Wan is a compound Chinese medicine consisting of Huang Bai, Radix Rehmanniae Praeparata, Radix et Rhizoma Polygoni Multiflori, Poria, Rhizoma Coptidis, Rhizoma Zedoariae, and so on, so it cannot be defined by cold and hot. Zhi Bai Di Huang Wan is a nourishing agent for kidney yin, with bitter taste and slight gas, it has the efficacy and effect of nourishing yin and lowering fire, it is mainly used for the treatment of hot flashes and night sweating caused by yin deficiency and fire exuberance (most of them are feverish in the late afternoon at regular intervals, sweating after falling asleep, and sweating stops after waking up from sleep), dry mouth and sore throat, tinnitus, spermatorrhea, and short and reddish urination (urine is small in quantity, dark in color, with pain in urination, etc.). Zhi Bai Di Huang Wan is an oral medication, its adverse reactions and contraindications are still unclear, the specific dosage should be used in strict accordance with the doctor’s instructions, so as to avoid adverse reactions in the process of using the drug. In addition, if Zhi Bai Di Huang Wan is to be used together with other drugs, a doctor should be consulted in advance to minimize the risk of using the drug. It is recommended that patients with discomfort go to a regular Chinese medicine hospital, by a professional Chinese medicine practitioner for dialectical treatment, choose appropriate and effective drugs for treatment, not blindly according to the medicinal properties of the drug of their own choice of drugs, so as to avoid treatment is ineffective, delayed condition.