Malignant tumors of the hepatic flexure of the colon and transverse colon vary in size and can be in the range of a few centimeters, but some patients are found late in life with lengths of up to 30 centimeters or even more. Malignant tumors of the hepatic flexure of the colon and the colon are usually detected when the patient has symptoms such as intestinal obstruction, and at this time, the tumor size in the patient’s body tends to be larger. However, different patients have different tolerance to discomfort and different discovery time, so the size of the tumor varies greatly. The early and late stages of malignant tumors of the hepatic flexure of the colon and transverse colon do not lie in the size of the tumor, but are mainly related to the depth of tumor invasion of the intestinal wall. Generally, early cancer cells only exist in the innermost layer of the intestinal mucosa, whereas in late-stage patients, the cancer cells have already spread to the peripheral lymph nodes or other parts of the body. When malignant tumors of hepatic flexure of colon and transverse colon are detected, the nature of tumor and lymph node metastasis should be clarified according to postoperative pathological examination to decide the next treatment plan.