Colds with yellow sputum and heavy nasal sound for a week are usually combined or secondary to bacterial infection on the basis of viral infection, and antibiotics such as amoxicillin capsules can be taken to fight infection, supplemented by phlegm removing drugs such as aminoglutethimide, acetylcysteine and other expectorants. Colds are caused by viral infections, most patients with viral infections will cause damage to the airway mucosa, thereby reducing local defenses, easy to secondary bacterial infections, followed by neutrophils phagocytosis of bacteria into pus cells, resulting in the appearance of yellow secretions, yellow sputum. At this time, the combination of bacterial infection can take amoxicillin capsules and other antibiotics for anti-infection treatment, at the same time, symptomatic supplementation with aminoglutethimide, acetylcysteine and other phlegm. If you have a cold with yellow sputum for a week and a heavy nasal sound, you should go to the hospital in time and follow the doctor’s instructions for medication, and it is not recommended that you use your own medication.