The normal range of total bilirubin is 1.7 to 17.1 μmol/L. 26.1 μmol/L is a mild elevation, which does not necessarily require treatment, and should be treated in conjunction with the cause of the disease. The normal reference range of total bilirubin is 1.7-17.1μmol/L (the specific value is based on the local hospital), the total bilirubin of 26.1μmol/L suggests that the total bilirubin is elevated, which is categorized into physiological and pathological elevation. Generally speaking, physiological elevation does not need treatment, while pathological factors need treatment, and the treatment should be formulated according to the specific disease. 1. Physiological factors: such as physiological jaundice in newborns, staying up late at night, strenuous exercise, long-term alcohol consumption and so on, can lead to elevated total bilirubin. This kind of situation generally does not need treatment, physiological jaundice of newborns will gradually return to normal with time, and other external factors can gradually return to normal after adjusting work and rest, quitting alcohol, and so on. 2. Pathological factors: such as paroxysmal sleep hemoglobinuria, hereditary spherocytosis, neonatal hemolysis, drug-induced hemolysis and other hemolytic diseases, and viral hepatitis, cirrhosis, hepatocellular carcinoma, cholangiocarcinoma, bile duct stones and inflammation and other diseases of liver and bile ducts, which can cause total bilirubin to be elevated. This condition needs to be treated for the cause. If the total bilirubin is elevated, it is recommended to consult a doctor in time to clarify the cause of the disease and carry out targeted treatment under the guidance of the doctor to avoid delaying the condition.